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From Richmond/Williamsburg/Newport News Area
- Take I-64 East to Exit 261B, Hampton Roads Center Parkway, NASA Exit
- Proceed to the end of the Parkway (approximately 1.8 miles), moving into the left lane
- Turn left onto Armistead Avenue towards NASA/Langley Air Force Base
- Go past the Langley Air Force Base West Gate, moving into the right lane (approximately 1.2 miles)
- Exit off Armistead Avenue to Commander Shepard Blvd. and the NASA Main Gate
From Norfolk Area
- Take I-64 West through the Hampton Roads Bridge Tunnel
- Remain on I-64 West to Exit 262B, Magruder Blvd.
- Remain on Magruder Blvd. through three (3) traffic lights, moving into the right lane
- Exit off Magruder Blvd. onto Commander Shepard Blvd. (Route 172 North, marked "NASA") (approximately 1 mile from last traffic light, and before the overpass)
- Remain on Commander Shepard Blvd. through the traffic light (approximately 1.2 miles), and you will be at the NASA Main Gate
From Isle of Wight Area
- Take Route 17 North over the James River Bridge (Route 17 become Mercury Blvd. at this point)
- Continue on Mercury Blvd. to the I-64 intersection (approximately 4 miles)
- Get on I-64, heading West; stay in the right lane on I-64 West to Exit 262B, Margruder Blvd.
- Remain on Magruder Blvd. onto Commander Shepard Blvd. (Route 172 North, marked "NASA") (approximately 1 mile from last traffic light, and before the overpass)
- Remain on Commander Shepard Blvd. through the traffic light (approximately 1.2 miles), and you will be at the NASA Main Gate
From Hampton
- Get on I-64 West to Exit 262B, Magruder Blvd., to NASA
- Proceed North on Magruder Blvd. (approximately 1.5 miles)
- Exit Magruder Blvd. at ramp to NASA/Langley Air Force Base, Route 172 North
- Continue on Route 172 North to NASA Main Gate (approximately 1.2 miles)
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